Targeted Therapy
Specialist in Aurangabad



Targeted Therapy


Targeted Therapy Specialist in Aurangabad

Targeted Therapy specialist in Aurangabad

Dr. Viraj Borgaonkar is a Targeted Therapy Specialist in Aurangabad at Krupamayi Hospital. He has more than 15 years of experience in Targeted Therapy treatments. You can visit Krupamayi cancer hospital in Aurangabad for the best cancer treatment.


What is Targeted Therapy?

Drugs that target specific elements of cancer cells, such as proteins or genes, that help tumors grow and spread, are known as targeted cancer therapies. They may also target other types of cells that help in the growth and spread of cancer. Targeted therapy may be more effective than other treatments for some forms of cancer.

The FDA has approved targeted therapy for over 15 cancers, including breast, prostate, colon, and lung cancers. However, they are only effective if your tumor has the correct target. Additionally, targeted therapies can stop working if the target changes or if your tumor develops a resistance to the treatment.



Are there different types of targeted therapy?

Targeted therapy comes in several different types. Monoclonal antibodies and small-molecule drugs are the most common forms.

Monoclonal antibodies are drugs that block a specific target on the exterior of cancer cells. The target could potentially be in the vicinity of cancer. Toxic substances can also be delivered directly to cancer cells via monoclonal antibodies. They can, for example, aid chemotherapy and radiation therapy in reaching cancer cells more effectively. Immunotherapy can also include monoclonal antibodies.

Small-molecule drugs. Small-molecule drugs can stop cancer cells from multiplying and spreading by blocking the mechanism. This sort of targeted therapy includes angiogenesis inhibitors. The process of angiogenesis is the formation of new blood vessels. Blood arteries are required to transport nutrients to a tumor. It can develop and spread thanks to the nutrients. Angiogenesis inhibitors starve the tumor by preventing the formation of new blood vessels in the surrounding tissue.

Other immunotherapies, angiogenesis inhibitors, and apoptosis inducers are examples of targeted therapy (therapies that start cell death, or apoptosis).

Some targeted therapies are tailored to a particular cancer type. Other treatments are referred to as tumor-agnostic or site-agnostic. They treat cancers in any part of the body by concentrating on the precise genetic change rather than the cell type. Learn more about treatments that are tumor-agnostic.



  • How does targeted therapy work?
  • Side Effects
How does targeted therapy work?

Every tissue in your body is made up of several types of cells. There are blood cells, brain cells, and skin cells, for example. Each type has a distinct function. When specific genes in healthy cells mutate and become aberrant over time, cancer develops. A genetic mutation is a term for this type of transformation.

Genes instruct cells on how to produce proteins that keep the cell functioning. When genes change, these proteins change as well. This can cause cells to divide excessively or too quickly, allowing them to live considerably longer than they would otherwise. When this happens, the cells become uncontrollably multiply and form a tumor. Learn more about cancer’s genetics.

Researchers must first discover the genetic modifications that help a tumor grow and evolve in order to design targeted therapies. A protein found in cancer cells but not healthy ones could be a potential target for this therapy. This can be caused by a mutation. Once a mutation has been detected, researchers create a medication that specifically targets that mutation.

Targeted medicines can affect cancer cells in a variety of ways:

  • Signals that tell cancer cells to grow and divide can be blocked or turned off
  • Stop the cells from lasting longer than they should
  • Cancer cells must be destroyed.
Side Effects

Targeted therapies have the potential to have substantial negative effects. Diarrhea, liver disorders such as hepatitis, and changes in your skin, hair, and nails are also common.

Skin issues are the most difficult for the majority of people to deal with. Because targeted cancer therapies target the same growth factors and blood arteries that are required for healthy skin, they occur. Keep an eye out for:

  • A rash on your scalp, face, neck, chest, and back that appears like acne. It could itch, burn, sting, or cause pain. It is possible it will become infected. It normally lasts the entire while you’re being treated, but it fades gone once the treatment is finished.
  • You feel as if you’ve had a terrible sunburn. This could begin before you notice any changes to your skin.
  • Sun sensitivity to the extreme.
  • Skin that is dry. It affects nearly everyone on targeted therapy. It’s possible that your skin will crack open, particularly on your hands and feet, making it difficult to use your hands or walk.
  • Sores on your fingernails and toenails are swollen and painful.
  • Hair loss or baldness, as well as sores on the scalp. After treatment, your hair may become an unusual color or fail to regrow.
  • It’s possible that your eyelids are red, puffy, and turning inward or downward. The cornea, the clear layer on the front of your eye, could be damaged as a result of this.


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